Unfortunately it doesn't seem to change anything with my first few tries. I used Comeback Kid as my test.
Using a fresh localization file, I have:
<?xml version="1.0" encoding="utf-8"?>
<save>
<header version="2" time="0" />
<version major="2" minor="0" revision="0" build="0" />
<region id="TranslatedStringKeys">
<node id="root">
<children>
<node id="TranslatedStringKey">
<attribute id="Content" value="abba" type="28" handle="hb15a53dbge70eg4ca7gba85g94f17e75c0e0" />
<attribute id="ExtraData" value="" type="23" />
<attribute id="Speaker" value="" type="22" />
<attribute id="Stub" value="True" type="19" />
<attribute id="UUID" value="ResistDead" type="22" />
</node>
</children>
</node>
</region>
</save>
"hb15a53dbge70eg4ca7gba85g94f17e75c0e0" is the handle corresponding to "Comeback Kid" in English.xml.
Note that I tried both "ResistDead" and "TALENT_ResistDead" for the UUID, as those were the only relevant looking things I could find in the .exe.