My preferred party in the previous patch (and I hope this still becomes possible in the full game) was a Jack of all trades mage: he did average damage, but he had a answer for any situation that the game threw at him (vit healing, armor healing, damage, cc, ect.) a dedicated mage healer that had access to all healing type spells and buffs but could do no real damage, a mostly pure back stab rouge (he had a couple magic spell like teleport, but his main focus was dps, and stealing), and a sword and shield magic knight (even split between magic and physical offense). This build wasn't possible in the current update, which was a bit frustrating considering it still is my dream way of experiencing DOS2 (part of why i replayed that patch so many times).
My build for the current patch was two enchanters, a knight, and a rouge. I found it could complete the journey, with little difficulty whatsoever, but I had barley any fun playing this way.