If you click on Profiles in the main menu, can you select the original profile (left click or the up/down arrow keys), so the text colour turns red, then switch by clicking the Select button or hitting Enter? What about creating a new profile, and then try switching to the original?
If you exit out of the game, you can manually delete the 'Debug_Client_Profile_1' profile folder in the '..\Documents\Larian Studios\Divinity Original Sin 2\PlayerProfiles' folder.
