Generally, the Debug_Client_Profile_1 profile is created if you start the game again when it is already running (to test something in co-op on a single computer, or create multiple custom party members).

Are you shutting down all non-essential programs (especially anti-virus) before starting the game? There are anti-virus programs that have interfered with D:OS and D:OS 2 creating or accessing folders in the My Documents folder.

If you click on Profiles in the main menu, can you select the original profile (left click or the up/down arrow keys), so the text colour turns red, then switch by clicking the Select button or hitting Enter?
Since you can create and use a new profile, you could just move all your saves over from the original profile's savegames folder.

If you exit out of the game, you can manually delete the 'Debug_Client_Profile_1' profile folder in the '..\Documents\Larian Studios\Divinity Original Sin 2\PlayerProfiles' folder.