For the random static noise, setting the game to run on a single core can also fix that.
One way to do so is to set it to run it in Win 9x compatibility mode (right click on the ..\SteamApps\common\divine_divinity\div.exe file, select Properties and switch to the Compatibility tab), or it can be done directly (start the game, Alt-Tab, right click on task bar and select Task Manager [Ctrl-Shift-Esc in Win7+], in the Processes tab, right click on div.exe and Set Affinity, then uncheck all but one core)
Sound issues?Sound cracklingOccasional audio hitches in Divine Divinity