Almost every time we launch game, debug profile loads
Generally, the Debug_Client_Profile_1 profile is created if you start the game again when it is already running (to test something in co-op on a single computer, or create multiple custom party members).
Are you shutting down all non-essential programs (especially anti-virus) before starting the game? There are anti-virus programs that have interfered with D:OS and D:OS 2 creating or accessing folders in the My Documents folder.
If you click on Profiles in the main menu, can you select the original profile (left click or the up/down arrow keys), so the text colour turns red, then switch by clicking the Select button or hitting Enter? What about creating a new profile, and then try switching to the original, rather than transfer saves?
If you exit out of the game, you can manually delete the 'Debug_Client_Profile_1' profile folder in the '..\Documents\Larian Studios\Divinity Original Sin 2\PlayerProfiles' folder.
If the problem persists after that, try starting the game directly from the '..\SteamApps\common\Divinity Original Sin 2\bin\EoCApp.exe' program file, by right clicking and running as administrator. If that makes a difference, right click the executable, select properties, switch to the Compatibility tab and set it to always run as administrator.
I basically tried everything you are suggesting, except for running it as admin. I also a have clean install of Windows 10 and my PC is exclusively used for gaming, so there isn't much software installed (basically Steam, Origin, GOG Galaxy). Restarting game, creating other profiles and trying to switch, etc - nothing worked. Only solution I found is to create a new profile and transfer saves and when this profile stops working, copy saves back to the original and so on.
I suggest removing the check alltogether or add option to force open anyway. What is the reason for this anyway? Average user wound not be able to solve this problem at all and will loose his saves.
