I always roam all the traders, especially those in Silverglen for Slow Immunity boots ...

(If you're not totally against it: the traders offers can still be 'save-scummed' to some extent ...)

You have tons of stuff you can do before heading to the desert, like Hiberheim and the Mines.
If you haven't done it yet: your best chance to get a full party wipe throughout all the game is probably Braccus Rex.