Personally, i'd use a 6 player-mod in a custom campaign without dialogs or that stuff, we'd roleplay all the conversations/decisions.
Problem would be the vignette system, or the roll call...things like that.
Guess it depends on how flexible the UI they designed is, if it can accommodate more than 4 and all that.
I hope the UI will be able support 6 players, because that would be fantastic. Some of us would like to play with 5 or 6 players and still be able to use all the features, after all.