The problem with saves crashing lies in levelcache files of your save. Haven't had a problem in the first act (levelcahce of Fort Joy was around 6 MB), in Reapers Coast when the total save size reached over 13 MB (~30 hrs of playtime), boom, 4 minutes loading screen and crashing when loading in-game.
So while hotfix might fix the further bloating of savegames, I wonder if they can do anything for existing saves.