[quote=HoppStyle]
Ingame dont use quicksave. always save manually and dont overwrite them. always use a new one.

This method is just temporary. That means you can play for like 2-3 hours befor it gets corrupted again. Every now and then again to your savefiles and check your latest file if its over 7mb or already 8mb. IF SO: delete them, use the method again and play again for few hours.

It works for me, maybe it'll work for you. [/quote]

So even if we dont quicksave and always save manually as a new savegame the game WILL get corrupted anyway?

Maybe (just maybe) the problem is saving itself at the moment.
If you noticed: If you save the game (quicksave or not) the screen will go grey for a short moment where you cant do anything, then the game goes back to normal BUT you can still read on the bottom right "Saving" and the notification that the game is saved comes a few seconds later.
The problem: You can walk, loot, talk, fight, sell, buy ect. while the game is still saving.

Coud this be the reason the save gets corrupted? Course you and the NPCs do "stuff" while the game is still trying to save?