I had this same issue. The engine would crash w/ a message stating mentioning something about Glasses not working.
After some investigation, I noticed the 'Divinity Engine Data' dlc had not completed its install yet. Open the Divinity Original Sin 2 Properties window > DLC tab > Divinity Engine 2 Data 'STATE' column. The state was 'Installing' for me.
After confirming the 'Divinity Engine 2 Data' finished installing, I was able to use the Divinity Engine 2 without anymore crashes from problems with 'Glasses'. I assume the root cause for my case were the missing or locked assets from the DLC while it was downloading.
Hopefully this helps someone. 'Glasses has Stopped Working' is a pretty vague error; there might be multiple causing it...