I don't object to anti-Lizard NPC's.
I object to getting quests and being unable to complete them as Lizard NPC's.
It's like getting a quest that needs Pet Pal to complete without Pet Pal; bad design.
But seeing how often when they boast freedom quests are extremely tightly made and require extreme arbitrary happens to actually finish (I'm thinking Witherspeere now) this is probably a status quo. That Larian really needs to work on. This is really bad design. I have yet to see a RPG that handles quests SO poorly, not even D:OS1 did this.