Couple of bugs on my playthrough:

Tarquin's scripts appear to have issues, particularly if you haven't finished an interaction/quest for him. After his long, original discussion in the Lady Vengeance hold, he introduces himself as if we'd never met at the beginning of Act 2. Then, after doing part but not all of his quest in Act 2, he introduces himself again at the beginning of Act 3 as if we hadn't met!

Beast's quest with the cursed ring from Act 1 doesn't want to close, even if the ring is long gone and the quest presumably impossible to finish.

The quest to kill Ryker stays open in later acts, even though it was turned in and the rewards pocketed.

The white magister (Jonathan?) holding Hannag's apprentice hostage transforms into the Hammer's Pet after he dies. I couldn't interact with the quivering figure, although I could drain unlimited amounts of source from him.

Note sure if it's a bug, but on Old is Gold, the character who originally got the quest to steal the three artifacts needs to interact with Cat to complete the quest, it won't let someone else trigger the option, or automatically take the items from another character's inventory.