I have successfully beaten all Larian games so far, from the original Divine Divinity to Original Sin, most of them on somewhat higher difficulty levels (where applicable).
Yes, this game is definitely not for point & click aficionados--it's not a Diablo II clone with nothing any more involved than clicking on things to kill them and automatically gathering loot. This is a real RPG in every respect. But if you finished OS 1 this game should be a breeze--I see very little in the way of fundamental differences between the two games, save that OS 2 is better in every way, imo. Something about your post doesn't ring true--because if you finished and beat OS1 on the "higher difficulty levels" (which don't increase the game's complexity but just make it easier for you to get killed and harder to kill things in a fight) you should have *no trouble* with OS 2.
None at all. Hopefully you didn't start this game on the highest difficulty mode...;) You sound like you should be playing in Story mode--and that you maybe are not following the story and completing quests and so on. I mean, doing those things is just like OS 1--just like it--so it's really hard to see you having these problems.
Now, you will from time to time invoke fights that you aren't advanced enough to win--and the way to handle them is to *go do something else* until you are strong enough to come back and win. I can say for certain that if you don't have the patience to advance your character in his skills then you never finished OS 1...;)