For me itemization is the least important bit in an rpg. What is important for me is combat and story (that specific order).
As one of the many who feels they get screwed over by the rng sistem I recomend this -remove all green and blue items from the game and give us more stat points and at least 1 rune slot per white. We should also have to farm gold like crazy for a white with 2 rune slots.