Running with the graphicSettings.lsx tweak for FakeFullScreenEnabled, using the most recent GoG release; had to launch directly from EoCApp with Lutris (added it manually).
Winetricks verbs used were xact, vcrun2015, d3dx9, d3dx10, d3dx10_43, d3dx11_42 and d3dx11_43, using Lutris' provided Winetricks script. (could not get it to work with provided winetricks from Manjaro repos and the normal Wine-Staging 2.18 via terminal, so that may be something to check out.)
Everything is running smoothly, besides the usual black book pages and buffs (mouseover tooltip works.)