Then we come back again to definition of RPG. RPG's essential part is role-playing your own or computer generated character. That meens that during course of his life his attributes improve.
This has hothing to deal with fantasy world and also with isometric perspective games. RPG can easily be sci-fi, FPS or third person shooter.
So, I can say that many such different games all belong to RPG genre: DeusEx, Heretic2 - btw. nobody mentioned theese great games <img src="/ubbthreads/images/graemlins/smile.gif" alt="" />, IWD, PST, Diablo, DD, DAOC, EQ, Morrowind, gothic, fallout. Even Warcraft 3 now has elements of RPG as heroes can acquire lvls and new abilities.