Well, let me give it a test too. Party all decked in lvl 16 gear. Lvl 15 encounter.
Lohse and Ifan instantly die. Red Prince and Fane die on their own turn due to the Piercing damage effect applied to them.
I easily beat it with cheese (offer up one superbuffed teammate, then let the rest join) since after that, no more challenge. Same with the RRjja-whatever godwoken Lizard Demon on Bloodmoon island, does an Arrow attack killing you instantly. She started hostile though, so I spawned an eagle and it took the damage, leaving a pathetically easy fight afterwards.
That's just bad design. Doesn't matter how "easy" or "balanced" it is with the known trick. Insta-kill then having to reload to surpass it is just... bad design.