The sorting bags would be #1 on my list. Everything I pickup is in open inventory until I review it. Once reviewed it goes in a specific bag, to Lady Vengeance or marked for sale. Keeps things clean until you need to find something in a bag, looks at the crafting bag.
Another UI sitch that gets me is when changing gear that has +Skill's on them.
Things dropped off your memorized skill list should be listed in the chat window.
Some way that if you are planning on changing X gear with X gear that have different +Skills associated, the system will tell you what skills you have memorized that would be affected. Lots of time spent looking this over.
There's a bug in the inventory craft screen that once you do one thing, it sets focus at the bottom of the window and nothing shows. You have to scroll up to see your inventory again or click a different cat and come back for it to re-calibrate.