Physical builds are king because physical attacks only need to break through armor, while magic attacks are up against magic armor AND resistances. Most physical builds have enough knockdown/atrophy/polymorph/cripple skills available to keep numerous enemies helpless for the entire fight.
Tanks may not aggro enemies like in standard games, but they turn into amazing support characters. You can use them to shape the battlefield; teleport enemies around, heal, buff, knockdowns, provoke, etc. Since the tanks are mainly ignored in this game that toon will be free to support the team so your damage dealers can maximize their turns. Every build can be successful if you utilize those skills properly and have a viable strategy for the fight.