A major bonus of strength based builds that is often overlooked is inventory size - especially when Lone Wolf-ing. I played a dual-mage Lone Wolf game and had annoyingly full bags all. The. Time. (2x100kg isn't a whole lot...), forcing me to either constantly return to base to vendor stuff off, or leave loot behind (something I find VERY hard to do *greedy bastard*). No such problems with my two handed warrior and his ranger sidekick. Fane alone can carry 780kg (lol), all the while one-shotting enemies in Arx with a single Overpower attack, or decimating entire groups on his own with Whirlwinds, Battlestomps, Blitz Attacks, and copious use of Adrenaline and Time Warp. Aetera spent her two turns of existence lying on her back (hur hur). Sallow Man never knew what hit him. Source Titan never got to move. Melee pointless? I beg to differ.
Now tanks, those do not work the way they do in, say, World of Warcraft. And I'm glad they don't. Why? Because the entire concept of the role makes no logical sense to begin with! Who in their right mind goes to attack the one enemy that is best suited to withstanding your attack, when you can just as well go for that squishy mage next to him? Y'know, the one that's hurting you more. The concept of sustained "tank aggro" may be a decent gameplay feature, but it is completely unrealistic. I like that enemies in this game aren't as stupid as their WoW counterparts. It helps immersion a lot.