There are less choices, then it might look.
One of the few real choices might be, which origins to pick. There you should decide on who you like the most after you talked to them. And you probably should decide, it you want a physical focused team setup or a magic one, though physical is more likely to be the better choice. Stats? There are no real choices (initiative gets screwed by round robin system) and skill trees? Surely less than it might look like.
One thing for sure: You should have a mystic scholar in team. And probably don't kill every NPC on sight.
After Act 1 you can respec at any time anyway, so missskilling is less of an issue anyway.
