If you email supportdos2@larian.com with the report.zip file generated by the
D:OS 2 Analysis Tool, along with a description (or link to this topic), I'll add that to the bug report for the issue I mentioned above. Hopefully that will help in figuring out what the problem is, since it has not been reproducible at this point.
Extract the zip file somewhere handy (like the Desktop) and in the AnalysisTool_DOS2 folder, run corresponding executable. It should detect the game install path, but if not you can browse to the 'Divinity Original Sin 2' folder. Optionally run the tests first, and then generate a report (it will be saved in the same location as the Analysis Tool).
The report will contain system and game information, as well as your saved games. To greatly reduce the file size, you can delete all of the saves from the zip (double click the zip file to open it in Windows Explorer, then browse down to the ..\Savegames\Story folder), since the issue isn't related to the saves themselves.