My concern is that one of the things Swen decides "doesn't work in a video game" from D&D rules is its combat system and he then replaces it with the combat system from the D:OS games. The D&D combat system and the D:OS combat system have nothing in common other than the very superficial claim that they're both "turn based."
I think that's also my primary concern when it comes to their adaptation of the 5e system.
I'm all for giving Larian free reins since it generally has resulted in some great games, but I don't want it to come at the cost of a 'diminished' experience where nearly all layers of depth, character builds and [combat] mechanics are removed or adjusted to make a more streamlined experience.