I cannot imagine how you can replicate 5e combat without misses. So many things are built around converting misses to hits and vice versa. Maybe they'll do the PoE thing and put grazes in, but how you then handle additional effects on hit is an issue. You can't have a fractional amount of incapacitation after being hit with a poisoned blade, for example. Unless you just make additional effects not proc on grazes, but at that point, why bother including the grazes at all, just make them misses.
Perhaps they'll have come up with something much cleverer than that though. Some sort of resource you can spend to auto-succeed on an attack roll? That would be an interesting way to handle inspiration, at least.
