There's been quite a lot of debate on the subject already, so get your umbrella out! At present nobody knows. There's much speculation based on this or that hint but we'll find out when we find out. And Larian will do their thing, and Swen might troll everybody, which he is of course entirely unknown for doing.
fwiw, I'd give the Original Sins a second chance. I'm also not a fan of turn-based isometric but still love the games in spite of that and it's about as isometric as you want it to be, with 360⁰ rotation and being able to zoom in until it's practically third-person. Albeit not very practical in combat but sometimes it's nice just to "be there".