I have the same problem. DD works fine, but BD doesn't (does it run on the same engine? do the modifications so much differ?). First off, you get a note, that your desktop isn't running in 16 bit color mode and that the game can be run that way, but may glitch, or become unstable (which eventually happens). DD doesn't give you that at all. Then comes loading (and saving as well) with it's screen somehow distorted/inverted colors or something, I've encountered this kind of behavior with Fallout 2, mostly in the main menu and the loading screens as well. The game itself worked and was pretty much stable, so a graphical glitch in a menu wasn't that big of a deal. But here it is an issue, when the game crashes in various places, or instances. I tried some compatibility modes, running as administrator and whatnot, even disabling those fullscreen effects or something, but no luck so far. The 4GB patch works wonders with D2: Developer's Cut (and just to make sure, it does work well with DD as well, eventhough not really needed there, but some GB of memory added never hurts), but seems not doing anything with my BD installation. I'm altering playing DD and D2: DevCut, but would love to play BD as well. Since this topic is still unanswered to this day, I'm trying my luck to resurrect it, maybe someone could find some solution.