Sorry to rez this post but I was having this same issue and the only work around I found was putting the game in Window mode. Fullscreen and Fake Fullscreen would cause the game to freeze after about 5 seconds. I could alt tab out and back in and the game would run for another 5 seconds. Window mode made the game playable. I had been playing on the same computer for awhile with no issues, I'm not sure if a GPU update caused this or what.