I'm in agreement with the first three posts. To latch onto the loot bonanza.. I'm generally not someone who favors streamlining or anything, but the inventory needs to be toned down for sanity reasons.

The amount of junk, useless stuff, crafting of useless stuff, etc. needs to be completely gutted. Even items that have a purpose need to be either combined or streamlined a bit to decrease the amount of stuff in inventories.

The teleporting abuse and inventory were two of my biggest gripes.