Yea, sure. We do have a camp site so I assume we will have to rest or be fatigued and the "sustinance" mechanic we're talking about could just be baked into that. As I said in my first post, having to empty your bladder every 3-4 hours is excessive and so would having to eat breakfast, lunch, dinner AND a late night snack every day.
Its about striking a balance with tedious and mundane things (that may also require micromanagement) and creative an immersive experience. If there are enough ammo/food or whatever supply to be scavanged from the surroundings or loot from dead bodies that you dont constantly have to go back to town and resupply its not an issue. Like, you rarely run out of normal arrows in Baldurs Gate because there are enough enemies around to kill that drops them.
Survival mechanics are notoriously difficult to balance in games not based entirely around them. They also don't really offer much interest. Press a button to search a container for some ingredients. Press a button to craft the ingredients into a thing you need. Press a button to use the thing you need.
If fulfilling their requirements is so easy as to be trivial through casual play, then they don't really add anything to the game except pointless busywork and could be discarded without consequence. If fulfilling their requirements is not trivial, then it's generally a distraction from other, more fun or interesting things that you would rather be doing.