It will always be there, because everything we do, we do based on our personal views and life choices. IE: Personal politics & agendas.
Most people saying 'Please don't add politics' are saying 'Please don't add something I won't like'. Because they don't want politics they don't like. If they agree with a statement, they probably won't even be aware that it was there at all.
We only take note of things we disagree with. It's kind of the human condition, sadly; we don't care, so long as it does not bother us.
No. It might seem difficult to distinguish and then broadly paint it all as the same thing(agenda) but it is not. The creator's comments or thoughts about the implementation quite often spills the beans. We see this all the time with movies these days.
I don't really like to get into this as I've learned to distance myself from "statement makers" over the years. I'll just leave it at saying that it's pretty easy to spot and is laid bare when the creator mentions "representation" as a reason for implementation. Again, like Bioware.
Larian can do whatever they want and I'm not one to object to that. I'm just giving them my two cents that going after a certain agenda be it "inclusivity", "diversity" or rainbow colours or whatever and using the game as a device to push that is not recommended as it usually comes at a cost of the RPG experience becoming lopsided.