There are lots of things to explore in the game on subsequent play through then just companion quest lines. The traits you choose can impact things as well. Some examples are Barbarian can be used to simply bluff your way to avoiding some fights. If you have the Outlaw talent, Papa Thrash (guarding the door to the undertavern of the Black Bull Tavern) will let you in due to a secret handshake. If you have the Soldier trait, the lizard (Warfare Vendor) in the elf cave at Fort Joy will heavily discount your trades with him. While these have minimal impact on the play through as a whole, discovering these different interactions can give subsequent a fresh feel to the play through.
Also, now that you are finished and know what frustrated you and gave you headaches, is there a character build you might want to try or party composition you want to try to make these easier? Perhaps you are correct, this may be the mentality of a mix/max player. Guilty as charged! 8^>
