What happens when you try leaving?

If you start a new game on explorer difficulty, and head straight to the clinic, as much as possible, to get the star stone there, do you have any problem entering and leaving the homestead?

Try clearing the cache (if that wasn't what you meant by resetting the memory):
- press and hold the Xbox button on the front of the console for 10 seconds until it shuts down
- unplug the power cable and wait 30 seconds
- plug the console back in and turn it on
- log into the same Xbox Live account you were using, start the game and let it sync, if required

Unfortunately, there is no way to get a save off the Xbox (other than MS's automated cloud storage), to be able to check it.