If you can kill that opponent quickly enough, it will bypass the second part of the fight (Rain + Thunderstorm, etc).

Try verifying local files: in the Steam library, right click on the game and select Properties, switch to the Local Files tab and then click on the 'Verify Integrity of Game Files...' button.
With the GOG version, in the (optional) Galaxy client, select Divinity: Original Sin 2 in the left column, then click on the More button, and in the Manage menu select 'Verify / Repair'. In Galaxy 2.0, select the game, then the settings icon at the top right (beside the Play button) and under Manage Installation select 'Verify / Repair'.

With the App Store version (or GOG without using Galaxy):

Terminal
cd ~/Library/Application\ Support\ ... up to the Divinity Original Sin 2.app folder
codesign -vvv Divinity\ -\ Original\ Sin\ 2.app

For the first command, it may be easier to browse to the install folder in Finder, then drag and drop the location into an open Terminal window (though for the App Store version the default install path is just in /Applications ).
The second command takes a while, and will output some lines starting with '--prepared' or '--validated'. If everything is fine, it will end with:

Divinity - Original Sin 2.app: valid on disk
Divinity - Original Sin 2.app: satisfies its Designated Requirement


If that doesn't help, please email supportdos2@larian.com with your save there (or email/post/PM a Dropbox or Google drive link, etc). If you are using any non-Larian mods, also include a list of those enabled and/or the modsettings.lsx file from your profile folder.
Each save is a folder in the '/Documents/Larian Studios/Divinity Original Sin 2 Definitive Edition/PlayerProfiles/<ProfileName>/Savegames/Story' folder.
For the App Store version, the path is: /Users/<UserName>/Library/Containers/com.larian.dos2/Data/Documents/Larian Studios/Divinity Original Sin 2 Definitive Edition/PlayerProfiles/<ProfileName>/Savegames/Story
In Finder you can zip a file or folder by right clicking on it/them and selecting compress.