I am having very consistent crashes that only started since the latest update. The first one occurs during the fight on the ship when Malady is casting her spell. The game consistently crashes at the end of Round 1. I then used a mod to start in Driftwood, and there the crash consistently happens near the end of the battle with the voidlings in the basement of the fishery upon killing the last bug with a fire immunity aura.
I have tried turning my graphics all the way down, playing in fake fullscreen mode, turning off audio, and reinstalling the game. I have also tried multiple profiles.