There are a lot of valid complaints about BG3, but even as an infinity engine baby, I can't really find the validity in this, as of the recent gameplay video.
You can see how much effort they went through to change the UI and make it its own thing, and while there are still holdovers here and there, given the progress they'd made by the Panel from Hell, I think it's pretty safe to assume this was a criticism they took pretty seriously, or at the very least something they had intended to work on since day one.
I don't want to illegitimize your complaint, though, I just don't understand what it would take for people to consider it to not look like a DOS2 reskin. Does it have to be 2D? Does it have to be RTWP in order to not 'look' like DOS2?
My biggest issue is that the game sounds like DOS2 a lot of the time, not so much that it looks like it.