There seems to be some bug with quests not updating after completing the required step.
Examples (in spoiler tags):
Masterwork weapon
Quest didn't update after I found and looted the Surrus Bark in the Underdark. I'm stuck in the "find Surrus Bark" step and the quest marker keeps following my character if I have the item in my inventory.
Nightsong
Quest didn't update after solving the moon circle puzzle in the temple and opening the door to Underdark. I went all the way in and the quest was still pointing me backwards to the moon puzzle room to "open the door". Updated only after I re-opened the door with the lever.