Two items:
1) If a character is casting an aiding/helping/boosting spell on a party member, it would be really nice if I could click the target's character portrait in the bottom left to target them.
2) I know the chaining system is from the DOS system. But I really think the game would benefit from a party selection system like BG 1&2 or RTS. Having the ability to drag my cursor and select characters either on screen or by portraits would make both investigating and combat setup much easier.