Right now I really don't like it.
When I want to check some skills or spells, 9 times out of ten it is for a specific character. As it stands I end up with not enough informations about the character I care about and 75% of the screen showing me useless content. The side effect is that every information has to be in a vertical column, so you always have to scroll to get to the section you want (and right now, as I'm not familiar with the fifth edition, the absence of tooltips or details is really hurting my understanding of the game but I guess they'll come later). With a fullscreen for each character, the character sheet could show the portrait (that I reaaaally miss), stats, skills and feats and have a zone where you show detailed informations about what you click or mouse over.
The individual inventory is simply nonsense, derives from multi-player and I hate it. Every time I want to swap party members (which happen a lot with only 4 slots in party) I have to manually move each and every item I want to carry over, it takes forever to search for a specific item and so on. It's nice having this design ready for the multi-player part, but don't hamper user comfort for what is supposed to be a single player experience first (if it designed for multi-player, I'd like to get my refund by the way, this isn't the game I bought). The only upside of individual inventory is to manage weight, but it's actually a non-existant gameplay issue. When you share inventory and take weight into account, you assume characters will swap items to accomodate for their respective carrying limitations, and the process is invisible and painless. With individual inventory, you simply put the burden of figuring out how to distribute items to the player, which is about basic maths and adds nothing gameplay-wise, and you just waste playtime.
The combat system seems okay so far, I feel like I can browse my options in a reasonable way but I also feel like I'm taking a lot of unnecessary steps to arrive at that result. Can't really pinpoint why right now, I'll try to pinpoint them later.