I took on the spider queen with levels 3. It's tough but manageable. You have to use stealth and place your chars next to the first phase spider. She must go down first round. Then the next one. Don't worry if the spider queen creates lots of small spiders. They are annoying but not very lethal. Make sure as well Lae'zel has lots of potions, especially speed and health, and you should be ok. As a side note, I had the sword of justice on Lae'zel and it helped a lot.
