1. Make sure to use expendables. A bunch of potions for big fights like that will make a difference.
2. I've seen people mention making use of the environment — I didn't d9 it, but burning spiderwebs is traditional in D&D...
3. I've got a ranger and picked a spider companion after facing tge first spiders. That plus Wyll's imp really helped keep the spawnwd spiderlings under control.