I, for one, hope not. DOS style crafting in BG3 doesn't fit in at all in my honest opinion. If anything, then crafting scrolls, potions and wands according to the rules as written would be fine.
I hope we don't end up with a crapton of clutter to be combined into nonsensical items. I'm not wearing a pot helmet again, even though it was hilarious in DOS 1. It's just not a D&D thing.