Thanks, this did help me!

My game was crashing every time I tried to do a long rest.
I had a different chest (the one from the burning village) that I'd sent back to camp to have Astarion open (he wasn't with me to unlock the chest).
But after he opened the chest in camp, all my saves were bugged.

Thought I'd lost ~60 hours of game play. Only lost about 3.