Couple of things to check here. As I had an issue at first with my desktop.
One: Check to see where your game is installed. If it is in the x86. Uninstall and move the game to the regular Program File location.
Two: Check your Video Card outside of game. Make sure all the settings use application defaults. Turn off anything that overrides application defaults.
Three: IF YOU CAN, run it on a Solid State drive.
Four: If you got it from steam, play in offline mode at first to get it to load up.
Let me know if you tried these and see where it lands you.
