I think it not even guidance well for me anyway... each time i reloaded trying to save Arabella.....it always falled me..... I reloaded the game 13 time and each time i have different target to pass and I failed all 13 time....with the same character buffed with guidance and sometime just not with guidance. Sometimes I would need 10 to succeed never secceed the roll and other time it would ask me for a 17-19 or even 20 to suceed in saving the girl.
If guidance works the way it has been explained in this thread, that would account for why you need various targets to pass on all your reloads. Failing them all regardless? I would have to recall how many rolls are needed and know what target was needed for each roll before I say if you were unlucky or not.