Not forgetting Anderson and his periodic "I was born in London", stated in a broad American accent. I've seen this explained away in that the accent was "lost" (his? All of them?) by the time of ME but no explanation for why a different accent was gained...
I mostly didn't pay too much attention and just expected that, it being an American game, most characters would sound American. As someone described it a while back, "the future is full of Americans and the past is full of Britons".
