One thing I do that helps with my hotbar, is to go into gameplay settings and go to the hotbar settings. It lets you customize which things are added automatically. I personally turn off everything besides spells, which means that only new spells i learn are added to my hotbar.

I haven't seen a hotkey for it yet, but in DOS they had the R and F keys scroll in between your hotbars. This let you group your different kinds of spells onto say, my melee damage spells or my utility spells. Once it's implemented, I feel like a decent way to group your spells would be to put 1st Level spells and major consumables on your first hotbar, and then use your other hotbars for corresponding spell levels.