I've just had a TPK in the tomb room with the fire-spitting gargoyle heads. Played it through many times with no bother, then managed to botch a Disarm roll and activated a head. I went to open the adjacent sarcophagus and managed to lose Shadowheart to the fire. Damn. Went to revive her and the rest of the party decided to follow. Boom, Sahdowheart couldn't get out in time and went down again, together with Astarion. As I turned to help Shadowheart again, Gale got in the way and Boom, we both went down.
I should have activated turn mode and unchained, but it shows how easily even someone who has played it through many times can get a TPK just by being complacent and not fully paying attention.
