Do your best to be super careful and stay stealthed at first; it gives you early warning of enemies you might not be able to see otherwise. Also, turning on npc outlines is a great boon!
Other than that, depending on where you're getting stuck, try taking a look around-- most of the plants are dangerous and interactable, and in the underdark there are cliffs everywhere to shove enemies off off if you've got a strong fighter!