I was just thinking of this when I heard we might be getting a werewolf party member. If given the chance with, I would infect my character with lycanthropy in a heartbeat. I just love werewolves.
Also, there are indeed Shifters in D&D 5e. As well as the Blood Hunters which are inspired by the Witcher series, they hunt monsters. However not official, but one of it's subclass is called Order of Lycan where you can play as a werebeast.